• MR SUNIL M BHOYAR
• MR NILESH M GHUGE
• DR SANJAY TOSHNIWAL

The present article includes recent advance in floating drug delivery system for designing and development of Metronidazole floating tablet to increase the bioavailability and therapeutic effectiveness of the drug using raft forming system. This article shows controlled release of metronidazole for proper duration of action at a particular site and is planned to prolong the gastric residence time after oral administration. The natural and synthetic polymers used are Sodium alginate, Xanthan Gum, HPMC, HPMC K4M respectively as a raft forming agent. The different formulation batches (F1-F10) were and formulated for physical parameter, Raft strength and in-vitro drug release. t

Key-words; Metronidazole floating tablet, raft forming agent

"FORMULATION AND IN VITRO EVALUATION OF METRONIDAZOLE FLOATING TABLET USING RAFT FORMING SYSTEM", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.9, Issue 3, page no.b404-b414, March-2022, Available :http://www.jetir.org/papers/JETIR2203154.pdf

"FORMULATION AND IN VITRO EVALUATION OF METRONIDAZOLE FLOATING TABLET USING RAFT FORMING SYSTEM", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.9, Issue 3, page no. ppb404-b414, March-2022, Available at : http://www.jetir.org/papers/JETIR2203154.pdf